ATT&CK analytic guidance
Processes that normally do not initiate network communications suddenly making outbound HTTPS connections with high outbound-to-inbound data ratios. Defender view: correlation between process creation logs (e.g., Word, Excel, PowerShell) and subsequent anomalous network traffic volumes toward common web services (Dropbox, Google Drive, OneDrive).
Processes (tar, curl, python scripts) accessing large file sets and initiating outbound HTTPS POST requests with payload sizes inconsistent with baseline activity. Defender perspective: detect abnormal sequence of file archival followed by encrypted uploads to external web services.
Office apps or scripts writing files followed by xattr manipulation (to evade quarantine) and subsequent HTTPS uploads. Defender perspective: anomalous file modification + outbound TLS traffic originating from non-networking apps (Word, Excel, Preview).
Abnormal API calls from user accounts invoking file upload endpoints outside normal baselines (M365, Google Drive, Box). Defender perspective: monitor unified audit logs for elevated frequency of Upload, Create, or Copy operations from compromised accounts.
ESXi guest OS or management interface processes establishing unexpected external HTTPS connections. Defender perspective: monitor vmx or hostd processes making outbound web requests with significant data transfer.